hi. im -not- trying to tell you what to do...its just that the effexor+remeron combination (nickname: California Rocket Fuel) has been studied a bit, so there's a little more data available on that than most other combinations.

have you ever tried Symbyax? Its zyprexa and prozac, in one pill. the other option would be to try a (I would think, low) dose of zyprexa along side however much prozac the doctor wants to prescribe. zyprexa by itself reduces agitation, anxiety, etc., but isn't great for depression. with prozac on board, the combination can help stabilize Bipolar I and treat "treatment-resistant depression," for a lot of people. weight gain and metabolic issues are potential (serious) problems, of course.

low doses of other "atypical" tranquilizers have been used, with some success. abilify, low dose risperidone, of course...seroquel. Seroquel can sometimes be effective all by itself in some cases of depression.

remeron has been used to boost a number of other antidepressants. wellbutrin, ssri drugs, effexor, cymbalta. i even read a patent online that involved using remeron at night w/ ongoing amphetamine treatment for people w/ severe depression and/or add/adhd on top of mood problems.

i hope you and your doctor can find something that helps w/o too many adverse effects.