I just started my second round of 6 shots (I do IM) and I feel it has helped me. I have PTSD, and really struggle with depression and anger. I did my first round in August, and although the effects were subtle, I felt much lighter, and had hope for the first time in a very long time. But the fires we had here in Wine Country were horribly stressful, and I slipped back down into the dark. Hopefully this second round will be as effective as the first. My daughter has also done it, and it has really helped her as well. I just wish it wasn't so expensive.