I am going thru this myself with my 17 year old. A couple of weeks ago we gave up trying to medicate her because she clearly let us know she had had enough. For the last week she has vomiting up even small amounts of foods enough four hours after fed her. She is not drinking that we can tell. Today she was able to keep down baby food, but not eating much. She is not purring even when I talk to her and ha not gotten of the bed for two days. Tomorrow we are going to the vet. I cannot put her through anymore, since our last try was so difficult and she was so upset. So no more pills medicine of any kind. If she cannot be helped with a shot and the vet has no doable ideas. I will euthanize her as better a week early than a day late. It has been absolutely gut wrenching to come to this decision, but she is having little if any enjoyment in her day. She has been such a good friend; I can't bear to not have her with me,but even more so cannot let her feel like crap everyday. It's not right and I think very selfish of me. Yet I amso sad.