Thanks everyone. I think Lithium is my pdoc's first choice before Depakote. Since depression is a problem for me and not just mania lately, maybe Lithium would be a good fit for me.......plus I am on Lamictal as a stabilizer. I'm still nervous. Maybe low-dose Lithium would be good. I know someone on high dose Lithium, and he was void of personality and all feeling. He was just coming out of the hospital though. We'll see.