I think it is something that you come to accept over time. At least I did. Early meds I gained some and hated it but swore I wouldn't pass a certain weight. But I didn't respond to med after med and there were fewer and fewer choices that didn't cause weight gain. So I gained weight and surpassed my limit. But by then I didn't care because it was better to have the weight gain than to be desperaely suicidal. And then Seroquel stopped and that meant clozapine which is one of the greatest wegiht gain meds there is. And I gained even more weight and again, I was ok because it was better than dying.

But I also reached a point this fall that I was able to lose some weight. I don't think I can or will lose all of it because it is very hard to trick my body into losing but I have lost about 15 lbs before having to take a break from dieting to deal with gallstones.

I do not agree that diet and exercise can prevent or control weight gain with all meds for all people (since we all react differently to meds). But achieving a point you can accept some weight gain to survive can happen and at least some weight loss is possible when you feel well enough and are able to be very patient with the process.