My pdoc also said that Klonopin can cause depression. This is why she won't raise my dose of Klonopin, especially since I've been really depressed. Out of anti-anxiety meds, I notice my mood is better on Ativan or Xanax, rather than Klonopin, but my pdoc does not like the short-acting effects of them, so I am kind of stuck. Klonopin helps me to a point, but I can't take it every day, or it will start causing me to feel more depressed. I think the added fatigue is something that plays a contributing role. I am on other meds that cause sedation, so Klonopin can make me more cranky and tired on occasion.