My T has, on occasion, said, "That's life" when I've related several annoying and/or horrible things that happened to me between sessions. Just one thing after another, some hard stuff I'd had to deal with, things that stressed me out, etc. I think she is rarely exasperated but when she is, she has said that. Once I remember her being quite short with me, although I don't remember what words she said. I got very quiet after that. Later that evening, she sent me an email to apologize, explaining why she was in a bad mood, etc. I felt better about it after that.