So my pdoc says I may (and I believe I probably will) have to add another medication to what I’m taking, as I have not successfully found a medication that has worked for me on one thing. I’ve been on 3 SSRIs and one SNRI. Two of the SSRIs I got off due to side effects and the other two pooped out. So now, I’m trying another SSRI. But I’m trying to figure out what else to add. I know, side effects are different for every person. Some side effects I can’t handle are weight gain and fatigue/tiredness. These become worse for me during depression, plus I have a medical condition that needs me to not gain weight.

In my mind, I would like to get my mood under control before any other thing like my fatigue or weight issues. So I’m thinking about adding an AP. I think Abilify would be good as weight gain and fatigue aren’t that common in terms of side effects. I would like to try a stimulant but I’m afraid about my anxiety increasing. I just know that a stimulant would help my hypersomnia and weight gain and concentration issues. Or I’m thinking about Wellbutrin, but am not sure if this interacts with Prozac (new med).

I will be talking this over with my pdoc though. Normally I get asked what to go on or am suggested a few things by her so. I just would like to hear about combinations that have worked or something that has not caused weight gain or tiredness. I’m just sick of depression at this point. I’ve been severely depressed for half this year already. I’m just kinda done with it all. Any advise is appreciated.

*Note: TRD means treatment resistant depression. It’s a form of MDD.