I've been on-and-off nearly everything for bipolar over the 13 years I've had the DX. I've been on three for 12 months now, one of those for 9 years and the sleep one for 5 years, but one of them is for sleep. It isn't working on its own, but I told my pdoc that I'm using hirsuta for sleep and she actually said "if it really is working, use it." She doesn't want me on more meds, and I don't either. I've also had to use other plant medicines for pain and PTSD from all the bad relationships I've had. I'm also having huge mood dips just about the same time the sun goes down daily. I use plants and supplements for that too, about an hour before dark. She knows and said "just be careful."