Well, this is the first time in a long time that I am trying a new medication... rexulti for bipolar depression. I am treatment resistant and have never responded well to antidepressants and am not taking anything at the moment although if rexulti by itself doesn't help I'll ask my pdoc if he will try me on an antidepressant again...

I stepped up from 0.5 to 1 mg a few days ago. Today felt pretty spacey in the middle of the day. Still taking a low dose of olanzapine but will get off that when I step up to 2 mg of rexulti. Olanzapine raises by blood sugar into prediabetes range but when i got off it last time, my blood sugar fell into normal range...

I am not having psychotic symptoms so that is good although my doom and gloom depressions are a kind of mild psychosis too; they just aren't seen that way by medical people because the thoughts are not that unusual in the sense that many depressed people have them and they are not grandiose and paranoid.

Please share if you have had experience with rexulti. I am hoping this medication will give me a bit of a lift without making me manic.