My pdoc has affirmed my opinion that the SSRIs and APs numb more than they actually relieve the depression. I definitely experienced the kind of non-feeling that you are describing when I was on multiple meds. Not the exact same combo, but about the same number. And like you, I tried many.

I have slowly tapered off most of my meds. From what I have read a slow taper is less likely to cause a rebound effect. It makes sense to me that if the meds change my body so that there is more seratonin floating around then my body will produce less. So when you go off the meds, it takes a while for the body to start producing more seratonin. The slow taper allows your body to gradually adjust, while a fast one may leave your body desperate for seratonin. Ditto for other meds and their effect.

I feel better off most of my meds.