I have been on Cymbalta 60mg as well as Wellbutrin 300mg for several months - I felt better but not 100%. My pdoc added Lamictal about a month ago (gradual titration up to 200mg daily) and now I feel better than I have in years. Even returning to activities I had stopped doing instead of sitting around and watched TV and eating. One of them seemed to curb my appetite a bit (or maybe just the fact that I am not trying to make myself happy with food), also sleeping less (I tended to sleep my depression away) but not so much that it is a problem. NIghttime sleep is appropriate.