I think the only thing I can say about this is that, back when I was on med's (Paxil is one I took), my experience was that as soon as I began taking the med, I felt an almost immediate positive effect. But as time passed, so did the uplifting effects. I just sort-of sank back into a state of what I'll term "neutral ennui", for lack of a better term. It's been a few days now since you posted this. Hope you're feeling better.