I do Weight Watchers and last August reached my 75 pound weight loss goal. This was in spite of some of the meds I'm on. I have to admit I gained 6 pounds over the holidays but am back on track now and hoping to get it off soon. Losing all that weight helped more than any antidepressant I've ever been on. Did it make my bipolar and mood swings go away? Of course not. But the fact that I actually started to like myself and the improved self esteem I have did wonders for my mental health.