The pattern for me usually goes like this.

1.) People meet me and wonder what the heck is wrong with me.
2.) As they get to know me, they become familiar with my history.
3.) Then they wonder how the heck I'm as sane as I am.

Before it gets to that point, however, there can be a lot of misunderstanding. When people first hear that I am little-to-no-contact with most of my birth family, I might get a lot of advice about "you only get one mother," or "family is important," or "forgiveness is for your own benefit," or "I'm sure your mother did the best she could." The more they learn, though, the more they understand.