It's Zoloft inhibiting the effectiveness of the Vyvanse/Dexedrine. The meds are a bit of a drug interaction, but he says just getting by with some amphetamine (even with lessened effect) is the better outcome because I do AWFUL without SSRI's. That being said, I HATE SSRI fatigue and sex dysfunction and elevated appetite (especially while in class or during certain places), but I cannot help the OCD and the panic attacks that come with the obsessions. It seems crazy to have me on amphetamines with all that, but I have really crappy metabolism (even worse) for methylphenidates, so I had zero luck with those. I actually felt even more OCD with those than I do with amphetamines (except for the end of the day), but I'd pick amphetamines any day over methylphenidates.