Also, the SNRI category was a complete and utter disaster for me. I tried Effexor XR, Pristiq, Wellbutrin, Straterra, and I've never felt worse. I never tried Cymbalta or Fetzima, but I don't think they would have been of any more help. I felt like crap on all their "relatives," so I didn't even bother plus I'm doing a hell of a lot better as Zoloft is always the answer for me every time.