I've been on Effexor since 1999, and it's worked well for me. I'm on a really high dose though 375 mg. normal therapeutic dose is 225 mg. I don't have any side effects from it. When I started it, I had some nausea and headaches, but they went away in a couple of weeks.

The only real negative I know of with Effexor, is it can be extremely hard to come off of, it's got a really bad discontinuation syndrome profile, but since I plan to be on it for a while, I'm not too worried about that.

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