I've been on it for awhile too, and it's worked well. I haven't had any side effects that I've noticed. But as splitimage mentioned, it's hard to come off of. If you need to stop taking it, you need to come off of it very slowly. Also, don't skip pills. When I've skipped two in a row or more I've gotten sick...and not just depressed sick. I felt horrible, but then within an hour of taking another pill I felt fine.