I was on Depakote for bipolar II for a year, year and a half. It did OK with my mood (though Lamictal is doing better), but:
The first 3 weeks I was on it, I puked my guts out.
When I washed my hair, handfuls would come out in my hand.
I had elevated liver enzymes.
I had unexplained bruising (which ultimately is what got me off it)
I don't remember what else, but I'm sure there was something -- I really didn't tolerate it well at all. And the withdrawal was a ******. Lasted about a month and I was so anxious I was ready to jump out of my skin.
Keep in mind that this is only MY experience. Everyone reacts differently to different drugs.
Candy
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