Yes, it absolutely is possible to lose weight while on seroquel, it just takes a bit more effort. Last summer, I decided to get serious about my weight, saw a dietician, and got serious about my food, and lost just over 30 lbs. I put some of the weight back on, but now I'm back to following my food plan, and am once again losing.
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"I danced in the morning when the world was begun. I danced in the moon and the stars and the sun". From my favourite hymn.
"If you see the wonder in a fairy tale, you can take the future even if you fail." Abba
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