Yes. I have moved to a place where I disliked it so much that I became depressed. I moved to that place because my then husband got out of the military and he got a job in said place. After 10 years in said place we divorced and I moved to another state.
I have also moved to a place I disliked in order to take care of my mother. Luckily for me, I ended up with a health problem and needed to move to another state to take care of myself.