That's a very nice problem to have!
I think if you've all ready contributed to the disaster relief and still want to give something to charity maybe seek out some local charity and give to them. Sometimes after major disasters everyone gives all their donations to one need and the small charities don't get as much as they usually do. Or you could do a few small personal surprise gifts to spread the joy and send flowers to someone like the babysitter or your secretary or someone you haven't seen in a long time like an old teacher.....or buy books for the children's library or a school......
I do think since the money wasn't expected you should enjoy it! At least some of it. Buy something beautiful for your new house or treat yourself to a little vacation or spa time.
I feel ashamed for having too much money a lot of times too although I have very little to be living in my country. But I don't think giving everything away is the best answer. My advice is ENJOY and don't feel guilty