I've had depression since Jr High School. I've been on a lot of different meds. It seems like it's working for awhile and then suddenly my depression is out of control again. I take 16 pills every morning, 2 at lunch and about half of the am dose for bedtime. I am soooooo tired of taking medication. I know I need it but I'm tired. I always feel depressed, every day, all day no matter what I do. I have "up" moments to make everyone think I'm okay but I'm feeling like I'm not. Any suggestion? I have a psychiatrist, a therapist, PCM, Neurologist, Rheumatologist, ENT, Allergy and Asthma, Audiologist, Podiatrist, Pain Management, Bariatric Surgeon and I think that's all of them.