I'm on 300 mg of Seroquel as the AP. We'll see if upping the Lamictal does anything. I go back to see him next week. I think perhaps he is trying to address the depressions I sometimes have, like a total meltdown last Sunday and feeling tired all the time. I have been on this amount of Seroquel for a long time, and while it makes me fall asleep (except when manic), I don't wake up feeling overtired when my meds are working right.