I'm on 300 mg Seroquel. I've been on low doses in the beginning (50 mg-100 mg) to sleep, and I did not gain any weight or have any side effects. At my highest I've been on 800 mg, so that's quite a range! I did not notice any significant side effects until being on 600 mg. I did manage, and it worked well when it comes to getting out of mixed mania., I had twitching and had to get a lot of sleep, or I would get light headed in the morning. My craving for sweets went up, but I only gained a little bit of weight. I felt sluggish, but I needed that to push me out of some horrible episodes.

The weird thing about Seroquel is that each dose is different. Below 600 mg, I experienced no weight gain, no twitching, no light headedness. However, I need at least 300 mg to notice any mood stabilizing properties. Otherwise, it is more for sleep. I get some fatigue and extreme sedation before bed, but that's it. Sleep is much better. It helped me think clearer and prevent racing thoughts/mania.

Anyway, I'm sorry that you've been IP. Sending you hugs.