I get an injection every other week. I have not noticed any negitive side effects. The positives are increased labido,little less depression and a slight increase in energy. The biggest pain is drawing the liquid out of the vial. If you end up going with injections ask for a larger needle to draw up the liquid then switch to a smaller needle to inject with you can use the shot needle to draw up the liquid it just takes a little longer but no big deal cause i have never been in a rush to get a shot lol. Good luck.