I'm going to go cliche big time here!

STOP RUMINATING ON WHAT YOU DIDN'T ACCOMPLISH AND FOCUS ON WHAT YOU DID DO AND WHAT YOU HAVE SURVIVED!

My big 6-0 is coming in a month and I feel much the same as you. I think it's normal to review your life and mourn the things you wanted but didn't do. But as for me, for a long time I had a lot of uncertainty as to where I'd be at this point in my life. I'm not where I hoped to be but I am in a good situation, and that's a lot more than I ever expected. I try to focus on the positive and what I now have rather than what I missed or didn't accomplish.

I hope you find relief for your female issues. (Have you looked into natural herbal treatments?) I never had major hormonal issues till I was well into perimenopause. I really did think I was going crazy for a while. But I survived it and came out the other side intact.

PM me if I can help you in any way.