Your sense of touch is your nerves. Everything is your nerves talking to your brain. Your brain tells your muscles what to do and your nerves tell your brain what's going on. That's why Mrs. Moggles couldn't feel anything when the doctor stuck her with a pin, her nerves are damaged all over.

Peripheral neuropathy is hands and feet, your peripheral (on the "outside"/farthest away from the center) body parts. It often is a result of diabetes as Mrs. Moggles says/has.

Autonomic neuropathy involves all the unconsious parts of your body that does stuff without you knowing and damage to those systems can cause trouble like this:

http://www.mayoclinic.com/health/aut...544/DSECTION=2

I found this:

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Though the terms neuropathy and polyneuropathy are often used interchangeably, polyneuropathy is more specific subset of neuropathy that implies a systemic process causing damage to multiple peripheral nerves.

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From: http://www.dejerine-sottas.com/about/glossary.php

and this:

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Polyneuropathy is a neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously. It may be acute and appear without warning, or chronic and develop gradually over a longer period of time. ...

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From: http://en.wikipedia.org/wiki/Polyneuropathy

I think polyneuropathy often occurs when your immune system mistakenly attacks your nerves like with this disease:

http://www.mayoclinic.com/health/chr...opathy/AN00288