I have been on Olanzapine on and off for years. I imagine depending on the dose, it can help with anxiety. My concern was becoming pre-diabetic. So IMHO your blood should be occasionally tested. BTW the combination of this with fluoxetine is used as one of the more effective treatments for BPers. Besides this combination handling depression and mania, I think the Olsnzapine enhances the effects of the AD. Actually the FDA approved of this combination to treat BP. FWIW