I've found that antipsychotics, unlike antidepressants, go to work quite quickly. As someone pointed out Seroquel can't be expected to work as an antipsychotic at such a low dose. Doses can go quite high into the 100's. It might though work as an bipolar antidepressant at your dose. It's FDA approved to, but I never found it did. I will say I found it to be mellower than other AP's I've tried.