This won't make you feel any better, but I didn't notice much change when I went from 40mg to 60mg. My understanding is that it's not considered a huge change for Latuda, if you can hold on until it's sorted out. Personally I wouldn't taper if you have enough left because then you'll be getting even less than 40mg some days. I've missed my whole Latuda dose more than once and didn't suffer.