Did you just start the Seroquel or have you been on it for a while? I ask because sometimes there can be restlessness caused by the med. I have akathisia from my med so I had my dose reduced and added another med to relax.

Do you have a sleep routine established? Any soothing guided meditations before sleeping? I usually go through and "clear my mind" before I sleep. There's also progressive muscle relaxation where you tighten and loosen groups of muscles starting from the feet and ending at the face.