yes I have donated plasma, some medications for bipolar stay in the blood even after it goes through the machines separating and cleaning system. if someone receives that plasma that still contains lithium or other bipolar meds it can be harmful. it used to be donation locations did not ask about health and meds and ended disposing the donated plasma, when testing the plasma for tissue typing and toxins. it costs donation centers money and time to collect and screen tainted or toxic donation due to medications, not to mention could leave their supply short on supplies if they keep having to dispose of it due to medications.

now they do screening for health and require doctors to fill out a form, the form usually asks what medications the person is on and whether removing plasma is harmful to that person.