Thank you for the clarification. I hope you understand that my asking those questions was because I didn't feel like I had the context of the situation so that helps.

There probably is something going on but there is a good chance it's not about you but something that's got her stressed or has her attention enough that possibly she wasn't entirely hearing you fully. it's been a 20 year friendship so I do believe it's probably unlikely that her inability to attend to you right now means its an end to the friendship.

Hang in there. Give it a good amount of time, because I am sure this is a very important relationship to you. don't make any rash decisions to end things or act impulsively...