Yes, I do use a pill box, a couple in fact. Somehow, 2 Seroquel halves ended up in my morning box. Then, I was thinking that’s funny, I usually only take one pill spilt in half in the morning (propanolol because it is cheaper to buy fewer 40 mg pills than more 20 mg pills), so then I put the 2 halves of Seroquel together in the morning. Ugh, that was miserable! I have to be more careful about which meds I take in the morning.