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Old May 19, 2018, 08:10 AM
Anonymous35014
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Yes, Lamictal can help with seizures; however, if one goes off Lamictal cold turkey (or titrates down too fast), they are at risk for getting seizures. That's the only potential downside. But there is no proof that you can get seizures from titrating up too fast. It's only the SJS rash risk that's been proven. But I've gone dir3ectly from 200mg to 300mg and had no issues. No SJS or whatever. (I'm on 400mg now, though.)

"Withdrawal Seizures: As with other AEDs, LAMICTAL should not be abruptly discontinued.
In patients with epilepsy there is a possibility of increasing seizure frequency. In clinical trials in patients with Bipolar Disorder, 2 patients experienced seizures shortly after abrupt withdrawal of LAMICTAL. However, there were confounding factors that may have contributed to the occurrence of seizures in these bipolar patients. Unless safety concerns require a more rapid withdrawal, the dose of LAMICTAL should be tapered over a period of at least 2 weeks (see DOSAGE AND ADMINISTRA TION)."

Source: https://www.accessdata.fda.gov/drugs...8s19s20lbl.pdf