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Old May 23, 2018, 09:20 PM
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Patagonia Patagonia is offline
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Member Since: Sep 2013
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Quote:
Originally Posted by mcl6136 View Post
Are you at all concerned that your own body produces pain-reducing substances that mediate complex biological processes -- and that supplementing them, via CBD and other substances -- could have serious, unforeseen consequences?


https://en.wikipedia.org/wiki/Endocannabinoid_system


I think anyone who takes these substances under the belief system that they have little or no downside....is simply kidding themselves and conducting an experiment on themselves with an unknown outcome.


Best of luck to you.


Well according to your citation from Wikipedia , which I’m not a big fan of due to citation issues it does touch on the affiliation of Anandamide.
Interesting....bec this is below is pulled from Wikipedia too.

...”It has been suggested that AM1172 could potentially be developed into a drug that would increase the brain's anandamide levels to help treat anxiety and depression.[28] Black pepper contains an alkaloid, Guineensine, which appears to be a relatively potent Anandamide reuptake inhibitor, thus increasing its physiological effects.”

Maybe this falls into the classic SSRI classification.
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