My Seroquel XR is so valuable to me. It has helped with my past manic, mixed manic, and depressive episodes. It is also helpful in calming my anxiety and agitation. Obviously it also helps me sleep. The XR is not that weight unfriendly for me, at least not nearly as unfriendly as other antipsychotics. It is also great in that it has never given me EPS of any sort, nor hyperprolactinemia. It might be a culprit in raising my cholesterol, but I try to eat low cholesterol to manage that.

My doses of Seroquel XR usually range from 350-600 mg depending on my mood situation. I think I might have once reached 800 mg of the regular a long time ago. That's my range. When I'm manic or mixed it goes up. Interestingly, when I'm depressed sometimes raising it helps and sometimes lowering it helps. It sort of depends on if the depression is very low energy or not and/or other characteristics. As an anxiety prn, a small extra dose like 50 mg can be helpful. I have even taken regular Seroquel prn for such things.

In my med mix of Tegretol XR, Lamictal, Klonopin, and Seroquel XR it is always the Seroquel XR dose that is manipulated, except for occasional prn Ativan.