black pepper aside, I am not a huge WIKI fan, either. Here is a crude explanation:

Your body makes substances called ENDO (inside) cannabinoids on its own. Just like it makes hormones like TSH (thyroid stimulating hormone) and other key ingredients to a balanced metabolism.

Your body's own cannabinoids are essential for well being and pain tolerance/relief.

Supplementing those substances with EXO (from outside your body) cannabinoids like CBD and pot...is a crap shoot, as far as I am concerned, and I would be very careful doing it long term.

Just as I would be very careful taking synthroid (synthetic thyroid drug)on a regular basis if I did not know that I had a thyroid disorder or how much I was taking or any of the side effects. I would also be very careful about supplementing my body with steroid compounds from outside my metabolism...because every day my body synthesizes many of these chemicals on its own.

People who take steroids to bulk up in weightlifting or cheat at cycling can suffer huge consequences down the line. CBD oil may seem like a miracle cure now but I think there are a lot of unanswered questions.