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It did for me. I was on doses ranging from 300-1500 mg with the higher doses mostly used for mixed episodes or depression. It worked for many years and then stopped and I changed to clozapine.
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Bipolar 1, PTSD, GAD, OCD.
Clozapine 250 mg, Emsam 12 mg/day patch, topamax 25 mg, ,Gabapentin 1600 mg & 100-2 PRN,. 2.5 mg clonazepam., 75 mg Seroquel and 12.5 mg PRNx2 daily
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