I agree with cln1812 that adjustments to meds vary. If you want to read other experiences, I'll share mine. Lamictal has only been activating for me. The very first time I took Lamictal I eventually became manic with major league energy from it. I remember feeling better than ever as it was eventually raised to 300 mg. I was also on Abilify at the time. After a while, the mania became severe enough for hospitalization. My medications we're charged.

The second time it was added after a very long severe depression for which I received ECT. After ECT relief my depression started to return. That depression was very stubborn. My meds were overhauled. After the initial switch, the new meds still struggled to completely rid me of the depression. That was when Lamictal was again added. By the time I reached 75 mg I felt stable. My psychiatrist then increased it to 100 mg, at which time I started to become delightfully hypomanic, so he added more antipsychotic. That created a most leveling situation. I've been on 100 mg Lamictal now for almost 8 years now, along with a high dose Tegretol XR and kind of high dose Seroquel XR. Seroquel XR has also helped with depressions over the years as well as manias. He never chose to increase my Lamictal because it can be so activating for me. For me, Seroquel XR manipulation seems to be safer.

One might ask why he keeps me on low dose Lamictal? Well, would removing it make it harder to fight future depressions? Adding it back would of course be a slow process. It's only one pill per day, which at one point was a hero. I regard all three of my medications as heros for me.