Depakote has knocked out full blown mania for me but does not help depression. I am only on 1000mg because my hair falls out at higher doses, plus I gain weight and my blood levels are acceptable at this dose anyway. I have not had liver problems. Usually that happens within the first six months. If you get past six months you’re usually good. Do keep up with the blood work though.

I’d recommend you give it a shot. Most of these medications have the possibility for horrible side effects but then most people may not experience them.