Hopefully the reduction in Seroquel XR will help. I wonder why your doctor doesn't try to first reduce, and see how it goes, and then add the Abilify, if needed. Who knows. Are you seriously sedated or depressed?

I understand the Seroquel XR "hangover", but I can say that it eased for me with a combination of patience and strategy. I try to never take my Seroquel XR later than 8 pm, if possible. I also try not to stay up that late at night. Ideally, if I take my Seroquel XR at 7 ish and go to sleep no later than 11 pm, I can get up with little problem at 6:30 am. Of course, my dose makes some difference in how sedating it is. Recently, I was fighting a mania and 600 mg plus my Tegretol XR and Klonopin at night helped ease the mania, but I was bright eyed and bushy tailed after 6 hours sleep. Time has passed, and I'm slowing down. I expect my psychiatrist to lower my Seroquel XR, but I doubt he will more than 100 mg. Maybe even just 50 mg. Honestly, that small reduction has made a noticable difference in the past. This may sound odd, but lowering my Seroquel XR has eased depressions in the past. Sometimes increasing it does, depending on its characteristics.

Slowed down I've had a little harder time getting up lately, meaning going to bed at 11:30 pm I get up around almost 7:30 am with a little annoyance. I've noticed sedation in the morning and early afternoon, but I energize a bit in the late afternoon and evening.

I've never taken Abilify with Seroquel or it's XR, but I took Abilify with Lamictal in the past. I know Lamictal is activating for me, but Abilify was either also activating for me, or not a powerful enough antimanic. That combo sent me severely manic with psychosis with two back to back hospitalizations. That's just my experience. For others, it's marvelous. I have a friend who says so. Plus, Abilify gave me akathisia, whereas Seroquel XR has never given me EPS or hyperprolactinemia. Seroquel XR is not as weight friendly as Abilify for me, but taking 400 mg Seroquel XR is somewhat weight neutral for me. Only at 600 mg do I get some cravings.

I'm happy not to be on more than one antipsychotic anymore. I am still on anticonvulsant moodstabilizers.

Sorry I write a lot. I type fast and love to "talk".