Of course that can happen, that all of us are just tiny quarks for a supreme ecosystem, but that's not life as we know it. All we know of life is that life is not possible without cellular organization. I would find an entirely different cellular organization (planets, for example) for the biggest ecosystem quite strange. But then again I do not hold a PhD.

I wonder, if the microorganisms living in us were to have intellect as much as we currently have as Homo sapiens sapiens, would they think we are the universe they live in? For each individual person.