Zyprexa is the glue that holds me together. I'm on a lot of meds but that one is the most effective IMHO. I'm on a low dose, but my pdoc is threatening to raise it if I don't start sleeping better and pulling myself out of this spring/summer hypomanic phase. It's probably time for a dose adjustment anyway; I've been stable on these meds for a couple of years but I think they're wearing out. I have been on Zyprexa for over four years and there's absolutely no indication that it's going away any time soon. I know docs don't like to leave people on multiple APs for long but it seems to be necessary for some of us.