here's the update after all of you responded with what works/doesn't work: seems our insomnia and meds affect all of us so differently; my previous good working combo was 5mg melatonin, 1/2 of 25mg seroquel and 15mg temezepam; then i felt it pooped out on me; the night before last i was so desperate i took 30 mg. temezepam, 5mg. ambien and finally after a few hrs., a small piece of xanax: NO SLEEP but i realize i could have overdosed but didn't but yesterday's depression from all those meds. kept me in bed all day, so hungover and weepy from what those meds did or didn't do for my insomnia: but last nite after hearing from you that melatonin sometimes doesn't work, i upped my seroquel to 25mg. and took 15 mg. temezepam and slept 9-1/2 hrs. and feel almost like myself again. for years sleep was never an issue, but now at 72, it seems like the last 2 years have been hell with the insomnia.