it really depends. the antipsychotics are also known as tranquilizers, so...if one can tolerate them w/o tics, twitches, akathisia, etc., then they can help anxiety and agitation.
with the older ones, i would think perphenazine might be a good idea. it was (is?) packaged with Elavil in one pill, to help some forms of depression (low dose perphenazine), or psychotic disorders with a strong depression component (the higher dose combo pills). in a big study, perphenazine did almost as well as Zyprexa in people with Schizophrenia, w/o the same level of metabolic problems, a tad more twitches and such.
loxapine is an older one that PET scans suggest might be "atypical" at low doses. higher doses...not much different from haldol.
amoxapine is a tca antidepressant that doubles (at higher doses) as a tranquilizer. its a tca, so not a good idea if you're suicidal or have heart problems. a former shrink swears by it for psychotic depression.
|