I'm doing 1200mg a day, 2x600mg. Jarrow makes quality stuff all around and their sustained release is great (I used to use it for hangover prevention) but it's so much more expensive that I'm just doing 2 doses of 600mg, morning and evening.

I haven't noticed a big change but I have other oxidative stress concerns beyond just bipolar so I will probably keep taking it regardless... but i've only been on it regularly now for 5 weeks or so, and med changes have been going on, etc etc. I thought she might have been a little quick on the draw on suggesting to reconsider it after only 4 weeks. I haven't read the studies in detail yet though for myself.

Have you heard of any negative side effects from it beyond the usual upset stomach type stuff? I can eat tons of NAC at once, empty or full stomach, no problem any which way. I feel like she was implying maybe systemic side effects or something but we didn't have time to get into it.