not an expert but...antidepressants tend to boost tranquilizer blood levels. i think sufficient doses of flupentixol can kill the sex drive, plus there's the potential for prolactin elevation.

antidepressants+antidepressants...I think one sees blood levels go up, too. I could be wrong, of course. with zoloft, that could=ssri type sexual dysfunction. with wellbutrin, that could=overstimulation, now and then a drug-induced seizure (not to scare you...much more common at high doses, like over 400).

im not you, im not your shrink, but...do you think you could have a chit chat about streamlining the line up? the doses of the individual drugs are fairly low, but cocktailing it means drug-drug interactions, plus higher acquisition costs, etc.

personally...just based on my own experience...id see about higher dose of the flupentixol, especially while you adjust to the wellbutrin, the see whether the effexor or the zoloft is more important to your well-being (obviously, this would invovle a talk with your shrink...).

again, personally, I'd take effexor over zoloft. as one ramps up effexor doses, it hits more parts of the brain, plus it has a wide dosage range. tapering can be a pain, though, more so than many other drugs for depression.

hope this helps.